ARNA Lab - INSERM U869

CAST Team

2007-present |  2003-2006 |  1999-2002 | 




2007-present

  • Barthelemy, P. (2009) Nucleoside-based lipids at work: From supramolecular assemblies to biological applications. Comptes Rendus Chimie 12, 171-179.   online Access

  • Khiati, S., Pierre, N., Andriamanarivo, S., Grinstaff, M.W., Arazam, N., Nallet, F., Navailles, L., Barthelemy, P. (2009) Anionic nucleotide-lipids for in vitro DNA transfection. Bioconjug. Chem. 20, 1765-1772.   online Access

  • Ceballos, C., Prata, C.A.H., Giorgio, S., Garzino, F., Payet, D., Barthelemy, P., Grinstaff, M.W., Camplo, M. (2009) Cationic nucleoside lipids based on a 3-nitropyrrole universal Base for siRNA delivery. Bioconjug. Chem. 20, 193-196.   online Access

  • Godeau, G., Barthelemy, P. (2009) Glycosyl-nucleoside lipids as low-molecular-weight gelators. Langmuir 25, 8447-8450.   online Access

  • Godeau, G., Bernard, J., Staedel, C., Barthelemy, P. (2009) Glycosyl-nucleoside -lipid based supramolecular assembly as a nanostructured material with nucleic acid delivery capabilities. Chem. Commun., 5127-5129.    online Access

  • Gissot, A., Di Primo, C., Bestel, I., Giannone, G., Chapuis, H., Barthelemy, P. (2008) Sensitive liposomes encoded with oligonucleotide amphiphiles: a biocompatible switch. Chem. Commun. 5550-5552.   online Access

  • Moreau, L., Camplo, M., Wathier, M., Taib, N., Laguerre, M., Bestel, I., Grinstaff, M.W., Barthelemy, P. (2008) Real time imaging of supramolecular assembly formation via programmed nucleolipid recognition. J. Am. Chem. Soc. 130, 14454-14455.   online Access

  • Chapuis, H., Bui, L., Bestel, I., Barthelemy, P. (2008) 2'-Lipid-modified oligonucleotides via a 'Staudinger-Vilarrasa' reaction. Tet. Lett. 49, 6838-6840.   online Access

  • Godeau, G., Staedel, C., Barthelemy, P. (2008) Lipid-conjugated oligonucleotides via "click chemistry" efficiently inhibit hepatitis C virus translation. J. Med. Chem. 51, 4374-4376.   online Access

  • Bestel, I., Campins, N., Marchenko, A., Fichou, D., Grinstaff, M.W., Barthelemy, P. (2008) Two-dimensional self-assembly and complementary base-pairing between amphiphile nucleotides on graphite. J. Colloid Interface Sci. 323, 435-440.    online Access

  • Gissot, A., Camplo, M., Grinstaff, M.W., Barthelemy, P. (2008) Nucleoside, nucleotide and oligonucleotide based amphiphiles: A successful marriage of nucleic acids with lipids. Org. Biomol. Chem. 6, 1324-1333.   online Access

  • De Jong, L., Moreau, X., Thiery, A., Godeau, G., Grinstaff, M.W., Barthelemy, P. (2008) Amphiphilic copolymer for delivery of xenobiotics: in vivo studies in a freshwater invertebrate, a Mesostominae flatworm. Bioconjug. Chem. 19, 891-898.   online Access

  • Prata, C.A., Li, Y., Luo, D., McIntosh, T.J., Barthelemy, P., Grinstaff, M.W. (2008) A new helper phospholipid for gene delivery. Chem. Commun. 13, 1566-1568.   online Access

  • Prata, C.A., Zhang, X.X., Luo, D., McIntosh, T.J., Barthelemy, P., Grinstaff, M.W. (2008) Lipophilic Peptides for Gene Delivery. Bioconjug. Chem. 19 (2), 418-420.   online Access

  • Campins, N., Dieudonné, P., Grinstaff, M.W., Barthélémy, P. (2007) Nanostructured assemblies from nucleotide-based amphiphiles. New J. Chem. 31, 1928-1934.   online Access

2003-2006

  • Grinstaff, M.W., Hernandez Prata, C.A., Meyers, S.R., Barthélémy, P., Li, Y., Luo, D., McIntosh, T.J. and Lee, S.J. (2006) Charge-Reversal Lipids for Gene Transfection. Molecular Therapy S206- S207.   online Access

  • Freville, F., Richard, T., Bathany, K. and Moreau S. (2006) Targeting of single stranded oligonucleotides through metal-induced cyclization of short complementary strands. Helv. Chim. Acta 89, 2958-2974   online Access

  • Moreau, L., Campins, N., Grinstaff, M.W., Barthélémy, P. (2006) A fluorocarbon nucleoamphiphile for the construction of actinide loaded microspheres. Tetrahedron Lett. 47, 7117-7120.   online Access

  • Bugaut, A., Toulmé, J.-J., Rayner, B. (2006) SELEX and dynamic combinatorial chemistry interplay for the selection of conjugated RNA aptamers. Org. Biomol. Chem. 22, 4082-4088.   online Access

  • Freville, F., Pierre, N. and Moreau S. (2006) Efficient stabilization of oligonucleotide duplexes through terpyridine metal complexes. Can. J. Chem. 84 (6), 854-858.   online Access

  • Cazenave, C., Bathany, K., and Rayner, B. (2006) Formation of N-branched oligonucleotides as by-products in solid-phase oligonucleotides synthesis. Oligonucleotides 16, 181-185.   online Access

  • Moreau, L.; Ziarelli, F.; Grinstaff, M. W.; Barthélémy, P. (2006) Self-assembled microspheres from f-block elements and nucleoamphiphiles. Chem. Commun. 15, 1661-1663.   online Access

  • Chabaud, P.; Camplo, M.; Payet, D.; Serin, G.; Moreau, L.; Barthélémy, P.; Grinstaff, M. W. (2006) Cationic nucleoside lipids for gene delivery. Bioconjug. Chem. 17 (2), 466-472.   online Access

  • Arigon, J.; Prata, C. A.; Grinstaff, M. W.; Barthélémy, P. (2005) Nucleic Acid complexing glycosyl nucleoside-based amphiphile. Bioconjug. Chem. 16 (4), 864-872.   online Access

  • Barthélémy, P.; Camplo, M. (2005) Functional Amphiphiles for Gene Delivery. MRS Bulletin 30 (9), 647.   online Access

  • Barthélémy, P.; Lee, S. J.; Grinstaff, M., W. (2005) Supramolecular assemblies with DNA. Pure and Applied Chemistry 77 (12), 2133-2148.   online Access

  • Dausse, E., Cazenave, C., Rayner, B., and Toulmé, J.-J. (2005) In vitro selection procedures for identifying DNA and RNA aptamers targeted to nucleic acids and proteins, in Oligonucleotide synthesis. Methods and applications (Herdewijn, P., Ed.) pp 391-410, Humana Press.   online Access

  • Bugaut, A., Bathany, A., Schmitter, J. M., and Rayner, B. (2005) Target-induced selection of ligands from a dynamic combinatorial library of mono- and bi-conjugated oligonucleotides. Tetrahedron Lett. 46, 687-690.   online Access

  • Barthélémy, P.; Prata, C. A.; Filocamo, S. F.; Immoos, C. E.; Maynor, B. W.; Hashmi, S. A.; Lee, S. J.; Grinstaff, M. W. (2005) Supramolecular assemblies of DNA with neutral nucleoside amphiphiles. Chem. Commun. 10, 1261-1263.   online Access

  • Moreau, L.; Barthélémy, P.; Li, Y.; Luo, D.; Prata, C. A. H.; Grinstaff, M. W. (2005) Nucleoside Phosphocholine Amphiphile for in vitro DNA transfection. Molecular BioSystems 1, 260-264.   online Access

  • Moreau, L.; Grinstaff, M. W.; Barthélémy, P. (2005) Vesicle formation from a synthetic adenosine based lipid. Tetrahedron Lett. 46 (10), 1593-1596.   online Access

  • Purse, B.W., Gissot, A. and Rebek, J., Jr. (2005) A deep cavitand provides a structured environment for the Menschutkin reaction. J. Am. Chem. Soc. 127, 11222-11223.   online Access

  • Lazzaro, F., Gissot, A., Crucianelli, M., De Angelis, F., Bruché, L. and Zanda, M. (2005) Reaction of Methylene Active Compounds with a Chiral Sulfinimine of Trifluoropyruvate: New highly Stereoselective Synthesis of (S)-α-Trifluoromethyl-Aspartic Acid. Lett. Org. Chem. 2, 235-237.   online Access

  • Gissot, A., Volonterio, A. and Zanda, M. (2005) One-step synthesis of O-benzyl hydroxamates from unactivated aliphatic and aromatic esters. J. Org. Chem. 70, 6925-6928.   online Access

  • Gissot, A. and Rebek, J., Jr. (2004) A functionalized, deep cavitand catalyzes the aminolysis of a choline derivative. J. Am. Chem. Soc. 126, 7424-7425.   online Access

  • Moreau, L.; Barthélémy, P.; El Maataoui, M.; Grinstaff, M. W. (2004) Supramolecular assemblies of nucleoside phosphocholine amphiphiles. J. Am. Chem. Soc. 126 (24), 7533-7539.   online Access

  • Prata, C. A.; Zhao, Y.; Barthélémy, P.; Li, Y.; Luo, D.; McIntosh, T. J.; Lee, S. J.; Grinstaff, M. W. (2004) Charge-reversal amphiphiles for gene delivery. J. Am. Chem. Soc. 126 (39), 12196-12197.   online Access

  • Gissot, A., N'Gouela, S., Matt, C., Wagner, A. and Mioskowski, C. (2004) NaNO2 -mediated transformation of aliphatic secondary nitroalkanes into ketones or oximes under neutral, aqueous conditions: how the nitro derivative catalyzes its own transformation. J. Org. Chem. 69, 8997-9001.   online Access

  • Gissot, A., Wagner, A. and Mioskowski, C. (2004) Buffer-Assisted, Selective Mono-C-Alkylation of Phloroglucinol: Application to the Synthesis of an Advanced Intermediate of Catechin. Tetrahedron 60, 6807-6812.   online Access

  • Becht, J.M., Gissot, A., Wagner, A. and Mioskowski, C. (2004) An Efficient Synthesis of Biaryls via Noncatalysed Anionic Coupling of an Arylsodium with a Haloarene. Tetrahedron Lett. 45, 9331-9333.   online Access

  • Bugaut, A., Toulmé, J.-J., and Rayner, B. (2004) Use of dynamic combinatorial chemistry for the identification of covalently appended residues that stabilize oligonucleotides complexes. Angew. Chem. Int. Ed. 43, 3144-3147.   online Access

  • Becht, J.M., Gissot, A., Wagner, A. and Mioskowski, C. (2003) Reinvestigation of the noncatalyzed coupling of aryllithium with haloarene: a novel aromatic nucleophilic substitution pathway. Chemistry 9, 3209-3215.   online Access

  • Zapata, L., Bathany, K., Schmitter, J.M. and Moreau, S. (2003) Metal-assisted hybridization of oligonucleotides, evaluation of circular 2 '-O-Me RNA as ligands for the TAR RNA target. Eur. J. Org. Chem. 6, 1022-1028.   online Access

  • Pileur, F., Andreola, M.L., Dausse, E., Michel, J., Moreau, S., Yamada, H., Gaidamakov, S.A., Crouch, R.J., Toulme, J.J. and Cazenave, C. (2003) Selective inhibitory DNA aptamers of the human RNase H1. Nucleic Acids Res. 31, 5776-5788.   online Access

  • Cherrak, I., Mauffret, O., Santamaria, F., Hocquet, A., Ghomi, M., Rayner, B., and Fermandjian, S. (2003) L-nucleotides and 8-methylguanine of d(C(1)(m8) G(2)C(3)G(4)C(5L)G(6L)C(7)G(8)C(9)G(10))(2) act cooperatively to promote a left-handed helix under physiological salt conditions. Nucl. Acids Res. 31, 6986-6995.   online Access

  • Belin, F.; Barthélémy, P.; Ruiz, K.; B., P. (2003) Use of new synthetic gallic acid derivatives as models for a comprehensive study of their anti oxidative activity. Helv. Chim. Acta 86, 247-265.   online Access

  • Dupont, A.; Eastoe, J.; Barthélémy, P.; Pucci, B.; Heenan, R.; Penfold, J.; Steytler, D. C.; Grillo, I. (2003) Neutron reflection and small-angle neutron scattering studies of a fluorocarbon telomer surfactant. J. Colloid Interface Sci. 261 (1), 184-190.   online Access

  • Barthélémy, P.; Chaudier, Y.; Tomao, V.; Pucci, B. (2003) Fluorocarbon Amphiphiles for Supramolecular Assemblies. In Self Assembly, Robinson, B. H., Ed. IOS Press: Amsterdam, The Netherlands, pp 80-91.



1999-2002

  • Barthélémy, P.; Tomao, V.; Selb, J.; Chaudier, Y.; Pucci, B. (2002) Fluorocarbon-Hydrocarbon non-ionic surfactants mixtures: a study of their miscibility. Langmuir 18, 2557-2563.   online Access

  • Chaudier, Y.; Zito, F.; Barthélémy, P.; Stroebel, D.; Ameduri, B.; Popot, J.-L.; Pucci, B. (2002) Synthesis and preliminary biochemical assessment of ethyl-terminated perfluoroalkylamine oxide surfactants. Bioorg. Med. Chem. Lett. 12 (12), 1587-1590.   online Access

  • Toulmé, J.-J., Dausse, E., Santamaria, F., and Rayner, B. (2002) Aptamers for controlling gene expression, in Pharmaceutical perspectives of nucleic acid-based therapeutics (Mahato, R., and Kim, S. W., Eds.) pp 89-120, Taylor & Francis, London and New York.

  • Vergé, S., Richard, T., Moreau, S., Richelme-David, S., Vercauteren, J., Promé, J.C. and Monti, J.-P. (2002) First observation of non-covalent complexes for a tanin-protein intercation model investigated by electrospray ionisation mass spectroscopy. Tetrahedron Lett., 43, 2363-2366.   online Access

  • Vergé, S., Richard, T., Moreau, S., Nurich, A., Merillon, J.M., Vercauteren, J. and Monti, J.P. (2002) First observation of solution structures of bradykinin- penta-O-galloyl-D-glucopyranose complexes as determined by NMR and simulated annealing. Biochim. Biophys. Acta 1571, 89-101.   online Access

  • Michel, J., Bathany, K., Schmitter, J.M., Monti, J.P. and Moreau, S. (2002) New ligand combinations for the efficient stabilization of short nucleic acid hairpins. Tetrahedron 58, 7975-7982.   online Access

  • Gissot, A., Becht, J.M., Desmurs, J.R., Pevere, V., Wagner, A. and Mioskowski, C. (2002) Directed ortho-metalation, a new insight into organosodium chemistry. Angew. Chem. Int. 41, 340-343.   online Access

  • Freund, F., Boulme, F., Michel, J., Ventura, M., Moreau, S. and Litvak, S. (2001) Inhibition of HIV-1 replication in vitro and in human infected cells by modified antisense oligonucleotides targeting the tRNALys3/RNA initiation complex. Antisense Nucleic Acid Drug Dev. 11, 301-315.   online Access

  • Toulmé, J.J., Di Primo, C. and Moreau, S. (2001) Modulation of RNA function by oligonucleotides recognizing RNA structure. Prog. Nucleic Acid Res. Mol. Biol. 69, 1-46.   online Access

  • El Amri, C., Mauffret, O., Santamaria, F., Tevanian, G., Rayner, B., and Fermandjian, S. (2001) NMR study of a Heterochiral DNA hairpin: impact of L-enantiomery in the loop. J. Biomol. Struct. Dyn. 19, 459-470.   online Access

  • Matt, C., Gissot, A., Wagner, A. and Mioskowski, C. (2000) Nitrolic acids: efficient precursors of nitrile oxides under neutral conditions. Tetrahedron Lett. 41, 1191-1194.   online Access

  • Mas, T., Susperregui, J., Berke, B., Cheze, C., Moreau, S., Nuhrich, A. and Vercauteren, J. (2000) DNA triplex stabilization property of natural anthocyanins. Phytochemistry 53, 679-687.   online Access

  • Arzumanov, A., Godde, F., Moreau, S., Toulmé, J.J., Weeds, A. and Gait, M. (2000) Use of the fluorescent nucleoside analogue benzo[g]quinazoline 2'-O-methylriboside to monitor the binding of the HIV-1 protein or antisense oligonucleotides to the TAR RNA stem-loop. Helv. Chim. Acta 83, 1424-1436.   online Access

  • Vichier-Guerre, S., Santamaria, F., and Rayner, B. (2000) Enantiomeric deoxy-L-nucleotides stabilize a Z-forming DNA decanucleotide. Tetrahedron Lett. 41, 2101-2104.   online Access

  • Sosunov, V. V., Santamaria, F., Victorova, L. S., Gosselin, G., Rayner, B., and Krayevsky, A. A. (2000) Streochemical control of DNA biosynthesis. Nucl. Acids Res. 28, 1170-1175.   online Access

  • Tosquellas, G., Bryksin, A., Alvarez, K., Morvan, F., Vasseur, J.-J., Rayner, B., Rykova, H., Laktionov, P., Vlassov, V., and Imbach, J.-L. (2000) Prooligonucleotides exhibit less serum-protein binding than phosphodiester and phosphorothioate oligonucleotides. Nucleosides, Nucleotides and Nucleic Acids 19, 995-1003.   online Access

  • Mauffret, O., El Amri, C., Santamaria, F., Tevanian, G., Rayner, B., and Fermandjian, S. (2000) A two B-Z junction containing DNA resolves into an all right handed double helix. Nucl. Acids Res. 28, 4403-4409.   online Access

  • Morvan, F., Vasseur, J.-J., Vivès, E., Rayner, B., and Imbach, J.-L. (2000) The oligonucleotide prodrug approach: the pro-oligonucleotides, in Pharmaceutical aspects of oligonucleotides (Couvreur, P., and Malvy, C., Eds.) pp 79-97, Taylor & Francis, London.

  • Michel, J. and Moreau, S. (1999) Use of C5-diamino-susbtituted-pyrimidine in triple helix forming oligonucleotides. Nucleosides & Nucleotides 18, 1633-1637.  

  • Morvan, F., Vives, E., Bologna, J.-C., Dell'Aqilla, C., Lioux, T., Vasseur, J.-J., Lefebvre, I., Rayner, B., and J.-L., I. (1999) Synthesis of fluorescent labeled lipophilic prooligonucleotides and their rapid and efficient uptake in HeLa cells., in Collection Symposium Series (Holy, A., and Hocek, M., Eds.) pp 135-140, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague.

  • Vialas, C., Pratviel, G., Meyer, A., Rayner, B., and Meunier, B. (1999) Obtention of two anomers of imidazolone during the type I photooxidation of 2'-deoxyguanosine. J. Chem. Soc. Perkin Trans. 1 1201-1205.   online Access

  • Vivès, E., Dell'Aquilla, C., Bologna, J.-C., Morvan, F., Rayner, B., and Imbach, J.-L. (1999) Lipophilic prooliginucleotides are rapidly and efficiently internalized in HeLa cells. Nucl. Acids Res. 27, 4071-4076.   online Access

  • Laurent, A., Naval, M., Debart, F., Vasseur, J.-J., and Rayner, B. (1999) Chiral and steric effects in the efficient binding of a-anomeric deoxyoligonucleoside N-alkylphosphoramidates to ssDNA and RNA. Nucl. Acids Res. 27, 4151-4159.   online Access



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Last update: September 15th, 2009